Professor Brian Huntly, Head of the University of Cambridge Department of Haematology, has been announced as one of fifty new Fellows elected to the Academy of Medical Sciences in 2021. The Academy of Medical Sciences is an independent body whose membership includes the UK’s best biomedical and health researchers. Following his election, Professor Huntly said […]
MRC-AMED Regenerative Medicine and Stem Cell Research Initiative awards
Three collaborative projects involving the Department of Haematology have receive funding from the MRC-AMED Regenerative Medicine and Stem Cell Research Initiative. A total of eight joint awards were made by the Medical Research Agency and the Japan Agency for Medical Research and Development (AMED) to projects focussing on regenerative medicine involving groups based in the […]
Stroma Biosciences selected for Accelerate@Babraham Start-up Programme
Stroma Biosciences is a spinout company founded by Dr Ingo Ringshausen and Dr Eugene Park from the Department of Haematology. It is working on the development of therapeutics targeting stroma-intrinsic mechanisms responsible for environment-mediated drug resistance and immune modulation in cancer and autoimmune disorders. Stroma Biosciences has been selected as one of four start-up companies […]
Clinical trial of stem cell-originated red blood cells to be launched
As featured in an interview and podcast for the Wall Street Journal, Dr Cedric Ghevaert will be leading the first-in-human clinical trial of red blood cells grown in the laboratory from adult donor blood stem cells. A randomised controlled Phase I cross-over trial titled RESTORE (Recovery and Survival of Stem Cell Originated Red Cells) based […]
Towards precision medicine: Funding awarded from the Rosetrees Trust for project focussing on myeloid cancers
Dr Jyoti Nangalia from the University of Cambridge Department of Haematology and Wellcome Sanger Institute has been awarded funding from the Rosetrees Trust for her project ‘Towards precision medicine: Integrating personalised prognostic predictions for patients with myeloid stem cell cancers into clinical care’. Dr Nangalia together with co-investigators Professor Brian Huntly from the Department of […]
Bertie Göttgens elected to membership of EMBO
Founded in 1964, EMBO is a pan-European organisation which aims to promote excellence in the life sciences and support talented researchers through all stages of their careers. It provides grants and fellowships, runs conferences and workshops and encourages scientific exchange between its members. Each year it accepts nominations for new members. No more than fifty […]
Uncovering the regulatory blueprint for early mammalian organ formation
In a Nature Cell Biology paper (Blanca Pijuan-Sala, et al, 2020, Single-cell chromatin accessibility maps reveal regulatory programs driving early mouse organogenesis), Professor Bertie Göttgens’s group has revealed new insights into the molecular regulation of mammalian organ development. Shortly after fertilization, the mammalian embryo generates so called pluripotent cells, which have the capacity to contribute […]
Targeting nearby ‘normal’ cells could improve survival rates
Republished from article written by Dr Ingo Ringshausen for The Conversation. Cancer of the immune system, called lymphoma or leukaemia, generally affects the entire body’s bone marrow and lymph nodes. Because these types of cancers are so widespread, surgery isn’t useful, so patients are usually treated with chemotherapy. Although these treatments have become […]
Insight into the development of lymphoma
Professor Brian Huntly’s team at the University of Cambridge Department of Haematology has shown that loss of CREBBP (CREB Binding Protein), a gene frequently mutated in human lymphomas, leads to the development of a pre-malignant stem cell population that evolves over time to ultimately give rise to full blown lymphoma. They have shown that […]
A BLUEPRINT for blood cells: major epigenetic study
Department of Haematology researchers have played a leading role in several recent studies looking at how variation in and potentially heritable changes to our DNA, known as epigenetic modifications, affect blood and immune cells, and how this can lead to disease. The studies are part of BLUEPRINT, a large-scale research project bringing together 42 leading European […]
Cambridge Blood and Stem Cell Biobank