Research in the department falls into three main areas with major relevance for human disease.

The Haematopoiesis and Leukaemia Group are based in the Cambridge Institute for Medical Research (Professor Green, Professor Göttgens, Dr Huntly, Dr Ottersbach) and the MRC Laboratory of Molecular Biology (Professor Warren).

The Structural Medicine and Thrombosis Group (Professor Read, Professor Huntington).

The Transfusion Medicine Group (Professor Allain, Dr Lee, Professor Ouwehand, Dr Ghevaert) are based in the NHS Blood and Transplant Building.

Recent research initiatives include the establishment of a $6.0M Specialist Centre for Research, funded by the US Leukemia and Lymphoma Society, the only one in Europe.

The department has also played a leading role in establishing a £5.8M European Bloodomics programme.