Clinical trials

Cambridge is a major centre for Haematology clinical trials. Haemato-oncology trials are supported by the Haematology Trials Team of the Cambridge Cancer Trials Centre (CCTC), a collaboration of Cancer Research UK, the University of Cambridge and Cambridge University Hospitals (CUH). The Haematology Trials Team is led by Lee Mynott (CUH Research Nurse and Team Lead) and Dr Faisal Basheer (CUH Haematology Consultant and Haematology Research Lead) and includes a team of research nurses and data managers, clinical research practitioners and pharmacists. CUH consultants are chief and principal investigators on a wide range of trials. We have a particular focus on acute myeloid leukaemia (e.g. VICTOR, Enhance-2, AML18), acute lymphoblastic leukaemia (e.g. ALLTogether), myeloproliferative neoplasms (e.g. Manifest, CABLO/ASCO4OPT, IMAGO), multiple myeloma (e.g. RADAR (Myeloma XV), MajesTEC-7, LINKER-MM3), lymphoma (e.g. CAPITAL, Mosunetuzumab Bispecific, REMODL-A, FLAIR) and bone marrow transplant (e.g. membership of the IMPACT stem cell transplant clinical trials platform). Other trials are supported by the Cambridge Clinical Trials Unit. A particularly important trial is RESTORE, the first in human trial of in vitro produced red blood cells, led by Professor Cedric Ghevaert. A list of current and recent trials can be found below.